Cancer Cachexia: Mechanisms and Clinical Implications
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چکیده
منابع مشابه
Cancer Cachexia: Mechanisms and Clinical Implications
Cachexia is a multifactorial process of skeletal muscle and adipose tissue atrophy resulting in progressive weight loss. It is associated with poor quality of life, poor physical function, and poor prognosis in cancer patients. It involves multiple pathways: procachectic and proinflammatory signals from tumour cells, systemic inflammation in the host, and widespread metabolic changes (increased...
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Fibrosis is the pathological condition resulting in the growth of excess fibrous connective tissue in an organ or body system as a reparative or reactive process. In the field of clinical pathology, clinicians and medical scientists are endeavoring to translate experimental knowledge into effective, innovative treatments for a range of fibrotic conditions. The amelioration of whole organ functi...
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Up to 50% of cancer patients suffer from a progressive atrophy of adipose tissue and skeletal muscle, called cachexia, resulting in weight loss, a reduced quality of life, and a shortened survival time. Anorexia often accompanies cachexia, but appears not to be responsible for the tissue loss, particularly lean body mass. An increased resting energy expenditure is seen, possibly arising from an...
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Cardiac cachexia (i.e. body wasting) has long been recognised as a serious complication of chronic heart failure (CHF) which affects many body systems and remains an important and increasing public health problem. The occurrence of wasting in CHF has been known for many centuries but little investigated. Independently of functional disease severity, age, and measures of exercise capacity and ca...
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ژورنال
عنوان ژورنال: Gastroenterology Research and Practice
سال: 2011
ISSN: 1687-6121,1687-630X
DOI: 10.1155/2011/601434